Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
The unpredictable behavior of uncontrolled type 1 diabetes often involves frequent swings in blood glucose levels that impact maintenance of a daily routine. An intensified insulin regimen is often unsuccessful, while other therapeutic options, such as amylin analog injections, use of continuous glucose sensors, and islet or pancreas transplantation are of limited clinical use. In efforts to provide patients with a more compliable treatment method, Oramed Pharmaceuticals tested the capacity of its oral insulin capsule (ORMD-0801, 8 mg insulin) in addressing this resistant clinical state. Eight Type I diabetes patients with uncontrolled diabetes (HbA1c: 7.5?10%) were monitored throughout the 15-day study period by means of a blind continuous glucose monitoring device.
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059524
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059524