CKD Patients with Diabetes Have Altered Gut Bugs

Status
Not open for further replies.

Northerner

Admin (Retired)
Relationship to Diabetes
Type 1
BOSTON -- Patients with chronic kidney disease (CKD) and type 2 diabetes had a significantly different make-up of gut bugs compared with healthy controls, researchers reported here.

In a small, ongoing study of 40 participants, those with CKD-diabetes were found to significantly higher levels of serum zonulin, and cytokines that affect inflammation. In addition, on the order level -- above genus and species -- the healthy controls had more Clostridiales, while the CKD-diabetes group had higher abundance of Bacteroidales and Acidimicrobiales, according to Tetyana L. Vasylyeva, MD, PhD, and Ruchi Singh, PhD, of Texas Tech University School of Health Sciences in Amarillo.

Clostridiales has been linked to metabolic syndrome, while Bacteroidales has been tied toinsulin resistance.

http://www.medpagetoday.com/MeetingCoverage/NKF/57631
 
Status
Not open for further replies.
Back
Top