Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Circadian misalignment decreases insulin sensitivity and increases inflammation, and is independent of sleep loss in men, according to a study published in the June issue of Diabetes.
Rachel Leproult, Ph.D., from the University of Chicago, and colleagues conducted a parallel group design study involving 26 adults. The authors sought to examine whether the misalignment of circadian rhythms that typically occurs in shift work involves intrinsic adverse metabolic effects, independently of sleep loss. The interventions involved three inpatient days with 10-hour bedtimes, followed by eight inpatient days with sleep restriction to five hours and fixed nocturnal bedtimes (circadian alignment), or with delayed bedtimes on four of the eight days with sleep restriction (circadian misalignment).
http://www.doctorslounge.com/index.php/news/pb/47217
Rachel Leproult, Ph.D., from the University of Chicago, and colleagues conducted a parallel group design study involving 26 adults. The authors sought to examine whether the misalignment of circadian rhythms that typically occurs in shift work involves intrinsic adverse metabolic effects, independently of sleep loss. The interventions involved three inpatient days with 10-hour bedtimes, followed by eight inpatient days with sleep restriction to five hours and fixed nocturnal bedtimes (circadian alignment), or with delayed bedtimes on four of the eight days with sleep restriction (circadian misalignment).
http://www.doctorslounge.com/index.php/news/pb/47217