Cellular 'stress sensor' could offer therapeutic target for diabetes

[Northerner]

An organelle called the endoplasmic reticulum (ER) helps to process newly synthesized proteins destined for delivery to the cell membrane. When the ER becomes overloaded and begins to accumulate poorly folded proteins, an 'ER stress' response ensues. ER stress tends to occur in obesity and other metabolic disorders. Now, research from Stephen Cohen and colleagues at the A*STAR Institute of Molecular and Cell Biology has revealed a potential therapeutic target linking ER stress to the onset of diabetes.

http://medicalxpress.com/news/2013-07-cellular-stress-sensor-modulates-metabolism.html