Cellular alchemy: How to make insulin-producing cells from gut cells

[Northerner]

Introducing three proteins that control the regulation of DNA in the nucleus -- called transcription factors -- into an immune-deficient mouse turned a specific group of cells in the gut lining into beta-like cells. “Our results demonstrate that the intestine could be an accessible and abundant source of functional insulin-producing cells,” says the lead author of the study. “Our ultimate goal is to obtain epithelial cells from diabetes patients who have had endoscopies, expand these cells, add PMN to them to make beta-like cells, and then give them back to the patient as an alternate therapy."

http://www.sciencedaily.com/releases/2014/03/140311141503.htm