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Admin (Retired)
- Relationship to Diabetes
- Type 1
A team of scientists at CSIR-Centre for Cellular and Molecular Biology (CCMB) in Hyderabad have discovered that genetic variants that increase homocysteine levels (biochemical molecule) in pregnant women can help predict low birth weight and future risk of obesity, diabetes and cardiac diseases in children.
In a research conducted for 20 long years, the scientists found that kids born to mothers with high homocysteine levels during pregnancy are obese and insulin resistant and have inferred that such children at high risk to develop diabetes in future.
According to the scientists, homocysteine is a key metabolite in one carbon metabolism that influences DNA methylation to regulate gene expression. Vitamin B12 and foliate are the major determinants in addition to several other factors like diet, smoke, stage of pregnancy for are responsible for increased homocysteine level in pregnant women.
http://www.pharmabiz.com/NewsDetails.aspx?aid=84859&sid=1
In a research conducted for 20 long years, the scientists found that kids born to mothers with high homocysteine levels during pregnancy are obese and insulin resistant and have inferred that such children at high risk to develop diabetes in future.
According to the scientists, homocysteine is a key metabolite in one carbon metabolism that influences DNA methylation to regulate gene expression. Vitamin B12 and foliate are the major determinants in addition to several other factors like diet, smoke, stage of pregnancy for are responsible for increased homocysteine level in pregnant women.
http://www.pharmabiz.com/NewsDetails.aspx?aid=84859&sid=1