Hi Caroleann, from the little I know about Byetta, it's a fixed dose, so I don't think carb-counting would come into it as you can't adjust the dose according to what you eat, like insulin, and there would be no ratios to apply at different times of the day. You might find that you have to adjust your diet though so that you achieve steady levels, so paying close attention to the type and quantity of carbs would be benificial.