Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Though existing research has shown gastric bypass surgery resolves type 2 diabetes, the reason has remained unclear. A research team, led by Nicholas Stylopoulos, MD, Boston Children's Hospital's Division of Endocrinology, has identified the small intestine?widely believed to be a passive organ?as the major contributor to the body's metabolism, based on a study in rats. The report will appear in Science on July 26, 2013.
Weight loss and improved diabetes often go hand-in-hand, but type 2 diabetes often gets resolved even before weight loss occurs after gastric bypass. To investigate why this happens, Stylopoulos and his team spent one year studying rats, and observed that after gastric bypass surgery, the small intestine changes the way it processes glucose. The team saw the intestine using and disposing of glucose; thereby regulating blood glucose levels in the rest of the body and helping to resolve type 2 diabetes.
"We have seen type 2 diabetes resolve in humans after gastric bypass, but have never known why," says Stylopoulos. "People have been focusing on hormones, fat and muscle, but we have shown in this study that the answer lies somewhere in the small intestine most of the time."
http://www.sciencecodex.com/boston_..._new_mechanism_for_diabetes_resolution-116430
Weight loss and improved diabetes often go hand-in-hand, but type 2 diabetes often gets resolved even before weight loss occurs after gastric bypass. To investigate why this happens, Stylopoulos and his team spent one year studying rats, and observed that after gastric bypass surgery, the small intestine changes the way it processes glucose. The team saw the intestine using and disposing of glucose; thereby regulating blood glucose levels in the rest of the body and helping to resolve type 2 diabetes.
"We have seen type 2 diabetes resolve in humans after gastric bypass, but have never known why," says Stylopoulos. "People have been focusing on hormones, fat and muscle, but we have shown in this study that the answer lies somewhere in the small intestine most of the time."
http://www.sciencecodex.com/boston_..._new_mechanism_for_diabetes_resolution-116430