BMI Is a Stronger Predictor of Diabetes (type 2) Risk Than Genetics

[Amity Island]

Body mass index (BMI) was found to be a more significant risk factor for diabetes (type 2) than genetic predisposition, according to research presented at the ESC Congress 2020

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Body mass index is a more powerful risk factor for diabetes than genetics

A person's Body Mass Index (BMI) is a more powerful predictor of whether they will develop diabetes than their genes, according to new research.

www.bhf.org.uk

 

[Eddy Edson]

... but not to say that genetics has no role:

“These findings indicate that BMI is a much more powerful risk factor for diabetes than polygenic predisposition, but a PGS can moderately improve estimates of lifetime risk of diabetes at all levels of BMI,” said Prof. Ference.

This part sounds consistent with Roy Taylor's "Personal Fat Threshold" concept:

Prof. Ference explained, “BMI appears to have a threshold effect rather than a cumulative effect on the risk of diabetes – the BMI level at which a person develops insulin resistance and hyperglycaemia is their diabetes threshold.” He continued, “The findings indicate that most cases of diabetes could be avoided, or reversed, by keeping BMI below the cut-off which triggers insulin resistance in each individual.”

“Both BMI and blood glucose level should be assessed regularly to prevent diabetes,” Prof. Ference concluded. “Furthermore, efforts to lose weight are critical when a person starts to develop hyperglycaemia as it may be possible to reverse diabetes by losing weight before permanent damage occurs.”

 

[Amity Island]

... but not to say that genetics has no role:

Very true!