Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a Rutgers study.
The study, which involved genetic analysis of mice, appears in the journal Cell Host & Microbe.
The findings suggest that newborns at risk for Type 1 diabetes because their microbiome -- the trillions of beneficial microorganisms in and on our bodies -- were disturbed can have the condition reversed by transplanting fecal microbiota from their mother into their gastrointestinal tract after the antibiotic course has been completed.
Type 1 diabetes is the most common autoimmune disease in childhood.
"Our previous work has shown that exposing young animals to antibiotics perturbs the microbiome, which may change age-associated immunity and organ-specific inflammation, increasing risk of immune-mediated diseases," said co-author Martin Blaser, director of the Center for Advanced Biotechnology and Medicine at Rutgers.
The study, which involved genetic analysis of mice, appears in the journal Cell Host & Microbe.
The findings suggest that newborns at risk for Type 1 diabetes because their microbiome -- the trillions of beneficial microorganisms in and on our bodies -- were disturbed can have the condition reversed by transplanting fecal microbiota from their mother into their gastrointestinal tract after the antibiotic course has been completed.
Type 1 diabetes is the most common autoimmune disease in childhood.
"Our previous work has shown that exposing young animals to antibiotics perturbs the microbiome, which may change age-associated immunity and organ-specific inflammation, increasing risk of immune-mediated diseases," said co-author Martin Blaser, director of the Center for Advanced Biotechnology and Medicine at Rutgers.
Babies at risk for diabetes may have microbiota restored
Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a new study.
www.sciencedaily.com