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Antibody levels in the blood of coronavirus patients drop quickly after the body clears the virus, according to a new study published in mBio, an open access journal of the American Society for Microbiology.
For convalescent plasma to help patients who currently have COVID-19, the donated blood needs to be collected soon after recovery. Under current guidelines, however, patients can't donate blood until 14 days after symptoms have resolved, and most donations occur even later.
"We don't want to transfuse the virus, just transfuse the antibodies. But at the same time, our work shows that the capacity of the plasma to neutralize viral particles is going down during those first weeks," Andres Finzi, PhD, one of the study authors and a microbiologist at the University of Montreal in Canada, said in a statement.
For convalescent plasma to help patients who currently have COVID-19, the donated blood needs to be collected soon after recovery. Under current guidelines, however, patients can't donate blood until 14 days after symptoms have resolved, and most donations occur even later.
"We don't want to transfuse the virus, just transfuse the antibodies. But at the same time, our work shows that the capacity of the plasma to neutralize viral particles is going down during those first weeks," Andres Finzi, PhD, one of the study authors and a microbiologist at the University of Montreal in Canada, said in a statement.
Antibodies in Recovered COVID-19 Patients Fade Quickly, Study Says
"We don't want to transfuse the virus, just transfuse the antibodies."
www.medscape.com