Anti-cancer properties of diabetes drug 'should be re-evaluated'

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Northerner

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Many clinical trials have looked to the use of metformin - a drug already used to treat diabetes - as a way of suppressing tumor growth in cancer by activating a molecule called AMP-activated protein kinase. But new research suggests that activation of this molecule may actually encourage tumor growth.

The study findings are published in the journal Proceedings of the National Academy of Sciences.

However, the research team, led by Dr. Biplab Dasgupta of the Division of Hermatology/Oncology at Cincinnati Children's Hospital Medical Center, says their study shows metformin can stop tumor growth, but through a process independent of AMP-activated protein kinase (AMPK) activation.

http://www.medicalnewstoday.com/articles/271139.php
 
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