Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
GPs have called for an urgent review of ?outdated' NICE guidelines on hyperlipidaemia after an analysis showed a 12-fold increased risk of severe muscle damage with simvastatin 80mg.
Researchers showed patients taking simvastatin across its doses were 2.6 times more likely to suffer rhabdomyolysis than patients taking other statins, in the first indication of a potential raised incidence of rhabdomyolysis in the community with simvastatin.
The findings follow the results of the UK SEARCH trial in 2010, which found a rate of rhabdomyolysis of 0.2% in patients taking simvastatin 80mg, compared with 0% in the simvastatin 20mg group.
http://www.pulsetoday.co.uk/newsart...-dose?sp_rid=NjU3NzMyNzAyOQS2&sp_mid=39129196
(free registration required)
Researchers showed patients taking simvastatin across its doses were 2.6 times more likely to suffer rhabdomyolysis than patients taking other statins, in the first indication of a potential raised incidence of rhabdomyolysis in the community with simvastatin.
The findings follow the results of the UK SEARCH trial in 2010, which found a rate of rhabdomyolysis of 0.2% in patients taking simvastatin 80mg, compared with 0% in the simvastatin 20mg group.
http://www.pulsetoday.co.uk/newsart...-dose?sp_rid=NjU3NzMyNzAyOQS2&sp_mid=39129196
(free registration required)