Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Adocia (Euronext Paris: FR0011184241 - ADOC) announces positive results from a phase IIa clinical trial evaluating its innovative ultra-fast formulation of insulin Lispro in comparison to Eli Lilly’s Humalog(R) commercial insulin. Adocia’s formulation incorporates proprietary BioChaperone(R) technology which enables accelerated absorption of prandial insulins. Humalog, which is now off-patent, has annual sales of USD 2.6 billion.
The present study met its primary endpoint, showing a significant increase in BioChaperone Lispro bioavailability in the first half-hour compared to Humalog. This parameter is critical as the ultimate goal for prandial insulins is an immediate absorption in the blood following subcutaneous injections. This result demonstrates that BioChaperone Lispro more closely mimics the endogenous insulin secretion observed in healthy individuals in response to a meal.
http://www.news-medical.net/news/20...haperone-Lispro-phase-IIa-clinical-trial.aspx
The present study met its primary endpoint, showing a significant increase in BioChaperone Lispro bioavailability in the first half-hour compared to Humalog. This parameter is critical as the ultimate goal for prandial insulins is an immediate absorption in the blood following subcutaneous injections. This result demonstrates that BioChaperone Lispro more closely mimics the endogenous insulin secretion observed in healthy individuals in response to a meal.
http://www.news-medical.net/news/20...haperone-Lispro-phase-IIa-clinical-trial.aspx