Northerner
Admin (Retired)
- Relationship to Diabetes
- Type 1
Diabetic kidney disease is perceived as the most serious long-term complication that inflicts the highest burden on people with type 1 diabetes. Approximately 10-15 percent of patients with kidney complications develop end-stage renal disease (ESRD), meaning that they need dialysis or a kidney transplant to survive. Current treatment methods rely on the proteinuria centered model, which utilizes the amount of protein in a patient’s urine to determine risk and treatment for kidney disease.
Despite the implementation of reno-protective therapies, drugs that reduce the amount of protein in urine, ESRD is still a prominent risk for people with type 1 diabetes, which is why Andrzej Krolewski, M.D., Ph.D., Head of the Section on Genetics and Epidemiology and Associate Professor of Medicine at Harvard Medical School, is implementing a new approach towards fighting ESRD. Dr. Krolewski’s approach focuses on the slope – or the rate at which renal function decline occurs – of renal function to assess and search for new therapies to treat ESRD.
http://blog.joslin.org/2016/03/a-new-approach-for-treating-diabetic-kidney-disease/
Despite the implementation of reno-protective therapies, drugs that reduce the amount of protein in urine, ESRD is still a prominent risk for people with type 1 diabetes, which is why Andrzej Krolewski, M.D., Ph.D., Head of the Section on Genetics and Epidemiology and Associate Professor of Medicine at Harvard Medical School, is implementing a new approach towards fighting ESRD. Dr. Krolewski’s approach focuses on the slope – or the rate at which renal function decline occurs – of renal function to assess and search for new therapies to treat ESRD.
http://blog.joslin.org/2016/03/a-new-approach-for-treating-diabetic-kidney-disease/