A ferry protein in the pancreas protects it from the stress induced by a high-fat diet

[Northerner]

Every time we eat, the glucose level in our body goes up. This spurs our pancreatic machinery into action and through intricate physiological mechanisms, appropriate amounts of insulin are produced, our blood glucose levels are controlled, and we remain healthy. But when a person indulges in high-fat food repeatedly over the long term, their pancreas is consistently overstimulated, eventually contributing to its damage and impairing its function. This increases the risk of developing type 2 diabetes, in which glucose level control mechanisms become lopsided.

Today, high-fat foods have become commonplace and so has diabetes. The need for designing new treatment strategies against diabetes is peaking. But to find an effective therapy, clarifying the causal cellular mechanisms at the core is essential. Now, a group of researchers from Japan, led by Dr Shoen Kume from Tokyo Institute of Technology (Tokyo Tech), have unraveled one key mechanism by which pancreatic function is regulated. Their findings are published in American Diabetes Association's journal Diabetes.

A ferry protein in the pancreas protects it from the stress induced by a high-fat diet

Scientists have now uncovered a key mechanism by which pancreatic function is maintained in response to a high-fat diet. A protein present in pancreatic insulin-producing cells protects them from damage under the stress induced by a high-fat diet. As the world increases its intake of high-fat...

www.sciencedaily.com

 

[Deleted member 21371]

It's an interesting finding.

 

[nonethewiser]

Unrelated to article, one meal enough for me to experience insulin resistance after eating high fat meals, wish it wasn't so.