Yes, Metformin can have an unpleasant side effect. Generally it's supposed to only last the first 2 or 3 weeks but for some people they don't loose the problem.
For me, I gained IBS for a couple of weeks and if I got my timing wrong (ie., took the pill an hour late). But after 6 months of the stuff my tummy is mostly behaving itself!
My Dr has said to take all at once is it better to be taking them 1 at each meal or what?
Its not how hard we hit. its how hard we can get hit and keep moving forward.