I don't disagree that sugar is an 'empty calorie' in that it has no value beyond the energy it gives (though sometimes some quick fuel is important.)
The rest I think is far less convincing.
His thesis that sugar (and HGFS) is a prime reason for the obesity crisis only makes sense with US stats. It doesn't hold up to scrutiny elsewhere in places where sugar consumption has fallen whilst obesity levels have soared.
In the US total sugar intake from 1980 -2003 increased by 23%. The intake of refined sucrose (sugar) actually dropped by 20% but this was more than made up for by an increase of 138% in the intake of other types of sugar notably high glucose fructose syrop (HGFS).
During the same period in Australia the consumption of sugar decreased by 20%, whilst at the same time obesity levels trippled. In the UK, , sugar intake dropped by 5%. whilst obesity levels more than doubled
Neither country consumes much HGFS.
The Australian Paradox: A Substantial Decline in Sugars Intake over the Same Timeframe that Overweight and Obesity Have Increasedhttp://www.mdpi.com/2072-6643/3/4/491/pdf