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Emerging Breakthroughs In Diabetes Treatment: A New Era Of Hope

Amity Island

Well-Known Member
Relationship to Diabetes
Type 1
Emerging Breakthroughs In Diabetes Treatment: A New Era Of Hope

For over 15 years, researchers at the Icahn School of Medicine at Mount Sinai have been at the forefront of diabetes research, striving to identify a drug capable of inducing the regeneration of human beta cells. In a significant breakthrough in 2015, they discovered harmine, a small molecule that is capable of stimulating beta cell replication. Esra Karakose, assistant professor in the Department of Medicine, is now studying the mechanism of action, and her team’s latest publication from an in vitro study suggests that harmine is inducing “fate conversion,” where alpha cells—another type of pancreatic cell—transform into beta-like cells capable of producing insulin.


 
Sounds interesting
 
Wow. Interesting, and also a benefit to type 2s where the beta cell mass/function is diminished.
Interesting that Alpha cells transform into cells that act more like beta cells. I believe in the development of a foetus a progenitor cell transforms into either beta or alpha cells.
 
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