Amity Island
Well-Known Member
- Relationship to Diabetes
- Type 1
Emerging Breakthroughs In Diabetes Treatment: A New Era Of Hope
For over 15 years, researchers at the Icahn School of Medicine at Mount Sinai have been at the forefront of diabetes research, striving to identify a drug capable of inducing the regeneration of human beta cells. In a significant breakthrough in 2015, they discovered harmine, a small molecule that is capable of stimulating beta cell replication. Esra Karakose, assistant professor in the Department of Medicine, is now studying the mechanism of action, and her team’s latest publication from an in vitro study suggests that harmine is inducing “fate conversion,” where alpha cells—another type of pancreatic cell—transform into beta-like cells capable of producing insulin.
www.forbes.com
For over 15 years, researchers at the Icahn School of Medicine at Mount Sinai have been at the forefront of diabetes research, striving to identify a drug capable of inducing the regeneration of human beta cells. In a significant breakthrough in 2015, they discovered harmine, a small molecule that is capable of stimulating beta cell replication. Esra Karakose, assistant professor in the Department of Medicine, is now studying the mechanism of action, and her team’s latest publication from an in vitro study suggests that harmine is inducing “fate conversion,” where alpha cells—another type of pancreatic cell—transform into beta-like cells capable of producing insulin.

Emerging Breakthroughs In Diabetes Treatment: A New Era Of Hope
From promising research to clinical-stage cell therapies and AI software updates, diabetes treatment and management is poised to change like never before.
